JCPM2022.07.26

Topics Discussed Include the Following…

*Botox for bruxism-the central effect
*PRP for peptic ulcer disease
*Botox for erectile dysfunction

Video/Recording of CMA Journal Club, Pearl Exchange, & Marketing Tips

Relevant Research, Relevant Links

BotoxClass.com<–

Research Review

The central nervous system effects of Botox and how those effects may benefit in the treatments of Bruxism and erectile dysfunction with Botox

Mazzocchio R, Caleo M. More than at the Neuromuscular Synapse: Actions of Botulinum Neurotoxin A in the Central Nervous System. Neuroscientist. 2015;21(1):44-61. doi:10.1177/1073858414524633
Caleo M, Restani L. Direct central nervous system effects of botulinum neurotoxin. Toxicon. 2018;147:68-72. doi:10.1016/j.toxicon.2017.10.027

ED

1.Abdelrahman IFS, Raheem AA, Elkhiat Y, Aburahma AA, Abdel-Raheem T, Ghanem H. Safety and efficacy of botulinum neurotoxin in the treatment of erectile dysfunction refractory to phosphodiesterase inhibitors: Results of a randomized controlled trial. Andrology. 2022;10(2):254-261. doi:10.1111/andr.13104

2. El-Shaer W, Ghanem H, Diab T, Abo-Taleb A, Kandeel W. Intra-cavernous injection of BOTOX® (50 and 100 Units) for treatment of vasculogenic erectile dysfunction: Randomized controlled trial. Andrology. 2021;9(4):1166-1175. doi:10.1111/andr.13010

Bruxism

Ågren M, Sahin C, Pettersson M. The effect of botulinum toxin injections on bruxism: A systematic review. Journal of Oral Rehabilitation. 2020;47(3):395-402. doi:10.1111/joor.12914

Fernández-Núñez T, Amghar-Maach S, Gay-Escoda C. Efficacy of botulinum toxin in the treatment of bruxism: Systematic review. Med Oral Patol Oral Cir Bucal. 2019;24(4):e416-e424. doi:10.4317/medoral.22923

Caleo M, Restani L. Direct central nervous system effects of botulinum neurotoxin. Toxicon. 2018;147:68-72. doi:10.1016/j.toxicon.2017.10.027

Renshaw cells (affected by BOTOX)<–

Research regarding the P-Shot® for ED<==

Treating peptic ulcer disease with PRP

Xu T, Tian Y, Wang Y, et al. Effects of Autologous Platelet-Rich Plasma on Healing of Peptic Ulcers: A Randomized Controlled Trial. M’Koma A, ed. Gastroenterology Research and Practice. 2022;2022:1-9. doi:10.1155/2022/7944849

Next Hands-On Workshops with Live Models<---

Question from Members

The current question I have is concerning a P-Shot, I administered on an 80 yr old male. He wanted to try it not necessarily for ED. But more for relief of urinary frequency. He has no history Of Prostate Cancer, his PSA levels are low, and < a week after the P-Shot®, he reported improvement in his frequency symptoms (2-3hrs versus q15 minutes). However, he now states his frequency has worsened (q30 minutes).

It has been 3 weeks since the procedure, and I told him we would continue to monitor.

Have you ever seen the P-Shot® relieve urinary frequency in men?

Relevant Links

–>Next class to learn to inject the major joints (knees, elbows, shoulders, Achilles) with PRP<–

–>Apply for Further Online Training for O-Shot®, P-Shot®, Vampire Facelift®, Vampire Breast Lift®, Vampire Wing Lift®, or Vampire Facial®<–

–>Next Hands-on Workshops with Live Models, worldwide <–

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